Oral Chelation and Nutritional Replacement Therapy for

Mercury and Other Heavy Metal Toxicity

By Maile Pouls, Ph.D. (Director of Research for Extended Health)

(Part 3 of a 3 Part Series)

Brief Review of Part 2:

The Chelation Solution. What is intravenous and oral chelation? Chelating (pronounced key-layting) agents are substances which can chemically bond with, or chelate (from the Greek chele, claw), metals, minerals, or chemical toxins from the body. The chelating agent actually encircles a mineral or metal ion and carries it from the body via the urine and feces. Intravenous chelation therapy involves injecting the chelating agent EDTA into the bloodstream for the purpose of eliminating from the body undesirable substances such as heavy metals, chemical toxins, mineral deposits, and fatty plaques. Chelation delivered orally involves ingesting nutritional food supplements which contain chelating agents (EDTA & numerous natural chelators) including; vitamins, minerals, amino acids, antioxidants, phytonutrients, and herbs.

Chelation and detoxification for metal poisoning & cardiovascular disease.

Chelation therapy with EDTA was first introduced into medicine in the United States in 1948 as a treatment for the lead poisoning of workers in a battery factory. Shortly thereafter, the U.S. Navy advocated chelation for sailors who had absorbed lead while painting government ships and facilities. The FDA approved IV EDTA chelation as a treatment for lead poisoning. Physicians administering the chelation for lead toxicity observed that patients who also had atherosclerosis (fatty-plaque buildup on arterial walls) or arteriosclerosis (hardening of the arteries) experienced reductions in both conditions after chelation. Since 1952, IV EDTA chelation has been used to treat cardiovascular disease.

Over 1,800 scientific journal articles have been published on the use of EDTA in intravenous (IV) chelation. In the past 30 years, hundreds of thousands of patients have received this therapy, as delivered by over 1,000 physicians in approximately 3,300,000 IV infusions. EDTA’s success rate in increasing blood circulation is 82%, provided the patients received sufficient chelation

Nutrients Known to be Protective Against Heavy Metal Toxicity:

Heavy Metal Protective Nutritional Supplement

Aluminum magnesium

Arsenic Amino acids (containing sulfur), calcium, iodine, selenium, vitamin C, zinc.

Cadmium Amino acids (containing sulfur), calcium, vitamin C, zinc.

Lead Amino acids (containing sulfur), calcium, iron, vitamin C, vitamin E, zinc.

Mercury Amino acids (containing sulfur), pectin (alginate), selenium, vitamin C.

All of these nutritional supplements and more are in the Oral Chelation and Longevity Plus formulas.

Part 3: Ingredients of the Oral Chelation Formula

1. Chelating agents: EDTA and nutrients that assist in the mobilization of metals and toxins; alginate, garlic (high allicin potential), activated attapulgite (clay), chlorella (freshwater algae; needed to bind up the liberated mercury and carry it out of the body via the feces), lipoic acid, methionine, and L-cysteine (heavy metal scavengers).

2. Antioxidants: Lipoic acid (extremely powerful, known as the “ideal antioxidant,” vitamin C, catalase, methionine, and L-cysteine.

3. Lipotropics (improves fat metabolism): Trimethylglycine, carrageenan, and L-lysine (blood vessel “teflon,” fatty plaque chelating agent, cellular fuel, reduces angina pectoris). L-lysine is an amino acid involved in the structural repair of damaged blood vessels. It has a beneficial effect on lead toxicity and high blood pressure.

4. Plant-based enzymes (bromelain, lipase, catalase): ensure optimal utilization of all of the above nutrients.

Ingredients of the Longevity Plus Replenishment and Antioxidant Formula

1. Chelating agents: Nutrients that assist in the mobilization of metals and toxins; Vitamin B1, vitamin E, bioflavonoids, cilantro, coenzyme Q10 (cellular fuel), L-glutathione, selenium, and zinc gluconate. Cilantro (Chinese parsley) has been shown in clinical trials and research to mobilize mercury, tin and other toxic metals stored in the brain and spinal cord and move them rapidly out of those tissues. This is a revolutionary discovery—cilantro is one of the only substances known to “mobilize” mercury from the central nervous system.65

2. Minerals: Calcium, magnesium, manganese, chromium, copper gluconate, molybdenum, potassium, selenium, vanadium, and zinc gluconate.

3. Essential vitamins: A (antioxidant, blood vessel stabilizer), D-3 (cellular fuel), E (antioxidant, chelator, blood vessel stabilizer, reduces angina pectoris), B1 (cellular fuel), B2 (cellular fuel), B3 (niacin [lowers cholesterol and triglycerides, cellular fuel, reduces lipoprotein] and niacinamide [cellular fuel]), B5 (lowers cholesterol and triglycerides, cellular fuel), B6 (cellular fuel), B12 (blood cell nutrient, cellular fuel), PABA, inositol, folic acid (blood cell nutrient, cellular fuel), biotin (cellular fuel).

4. Liv-1 (artichoke hybrid): an effective, powerful ingredient for detoxifying the liver during chelation, normalizing liver metabolism, and preventing further damage due to internal and external toxins such as alcohol and environmental poisons. It has antioxidant and anti-inflammatory qualities. Liver is the body’s filter for toxins. When the liver cannot keep up with the toxic load, toxins accumulate in that organ. This ingredient helps clear toxins out of the liver, including during both phase 1 and phase 2 liver detoxification (conjugation for water solubility and excretion), which most programs and formulas do not address.

5. Antioxidants: bioflavonoids, catalase, coenzyme Q10, Ginkgo biloba, grape seed OPCs (oligomeric proanthocyanidins), green tea, hesperidin, lutein, lycopene, quercetin, rutin, L-taurine, and 14 others.

6. Phytonutrients: hawthorn berry (cardiac tonic), iodine (as kelp; thyroid and energy production support), milk thistle and beet juice powder (support liver in detoxification and cleanse blood), and MSM (methyl sulfonyl methene; increases blood vessel elasticity), among others.

7. Amino acids: L-choline, L-carnitine (lowers cholesterol, triglycerides, cellular fuel), L-proline, and L-taurine (supports heart muscle and function).

8. Lipotropics: chondroitin sulfate. A constituent of the arterial wall, possessing anti-coagulant (reduces blood-stickiness), anti-lipemic (anti-fat in bloodstream), and anti-thrombogenic (reduces clotting) properties.

9. Plant-based enzymes: bromelain, lipase, catalase.

Note: In-depth information on formula ingredients is available upon request.

Summaries of Clinical Studies on the Oral Chelation and Longevity Plus Formulas

Note: Copies of the full studies are available upon request.

• In 1998, as Director of Research for Extended Health, I conducted heavy metal urine analyses on 14 patients, ages ranging from 29 to 73 and from a variety of different occupations, before and after only one day’s dose of the Oral Chelation and Longevity Plus formulas. Omegatech, King James Medical Laboratory, Inc., in Cleveland, Ohio, analyzed the urine samples.

The results showed significant excretion of all six of the heavy metals most commonly encountered and damaging to health. The following are the average percentages of increase in the 14 patients’ heavy metal excretions after just one day on the formulas:

Aluminum: 229%

Arsenic: 661%

Cadmium: 276%

Lead: 350%

Mercury: 773%

Nickel: 9,439%

• Hair analyses. Through Great Smokie’s Diagnostic Laboratory, we conducted on two patients before oral chelation and after six months on the program showed significant reduction of heavy metals. In one case, a dentist who had high exposure to mercury, the second hair analysis showed a decrease or a normal reading in all heavy metals that were abnormally high on the first hair analysis, except for mercury which was higher. In the other case, a dentist hygienist, the second hair analysis showed a decrease or a normal reading in all heavy metals that were abnormally high on the first analysis, except for silver, which went higher.

Heavy metals can be stored deep in the tissues, brain, and nerve ganglion. When all heavy metals except one decrease after chelation, we know that this one was stored at the deeper levels and is finally being pulled out of those tissues and mobilized for excretion. Thus, the higher readings are a positive sign that chelation is under way. In individuals with chronic or long-standing exposure to high amounts of heavy metal, the hair analysis readings can remain high and even go higher for a period of six to twelve months depending on the amount of previous exposure.

Mr. Bob Smith, Vice President of Elemental Analysis, Great Smokie’s Diagnostic Laboratory, who has interpreted the hair analysis of many thousands of patients, stated that, in his professional opinion, “your results exhibited significant reduction of heavy metals in just six months.”

• A medical doctor in Alamo, California tested one of his patients who took the Oral Chelation and Longevity Plus Formula with no other supplements or medications. After only two months of this regimen, blood tests showed significant reduction of triglycerides and LDL cholesterol and an increase in HDL cholesterol.

• Philip Hoekstra III, Ph.D., a pioneer of thermology, conducted thermological studies on six patients before they began taking the Oral Chelation and Longevity Plus formulas (no other supplements or medications) and after six months on the program. The study was conducted over the past years, under the auspices of the California Preventative Medicine Foundation in San Rafael, California.

Thermology is a diagnostic imaging based on measurements of heat emissions from the body filmed by infrared sensing devices and projected onto a computer monitor. Cells emit heat in the course of energy conversion. If there is a disturbance in the energy-conversion processes, as occurs in the case of blocked or narrowed arteries, the lessened heat emissions and reduced blood flow appear as darker areas on the thermology scan. In this way, thermology tracks the progressive deterioration of the flow of infrared energy along atherosclerotic arteries and can be used as early detection of heart disease.

The results of Dr. Hoekstra’s study revealed marked improvement in blood circulation in all but one of the patients, as documented by the thermologic images. Vascularization (improved blood flow) of the feet increased by as much as 33%—significant improvements after only a six-month trial.

Nancy Gardner Heaven, director of the Foundation, states, “It appears that even though the clients selected for this study had varying complex heart conditions, all but one had an improvement of at least a 20% increase in circulation, reducing the level of stenosis [narrowing] of the vascular system. I feel very good about recommending the use of this product [Oral Chelation and Longevity Plus formulas] to my patients with cardiovascular disease or a family history where prevention is an issue.”

Patient Reports on the Oral Chelation Program

In my private practice, I currently have 85 patients with a variety of health concerns who are taking the Oral Chelation and Longevity Plus formulas. They report improvement in the following conditions: headaches, cold hands or feet, skin problems, and degenerative diseases such as diabetes, autoimmune disorders, arthritis, and angina pains. They have also experienced positive effects in symptoms and conditions related to energy level, overall stamina, memory (forgetfulness), ability to concentrate, circulation, blood pressure, cholesterol and triglycerides, vision, respiration, and sexual drive or stamina.

The following are reports from three patients:

• Diana Goolsby, 36, and her son Landon, 3, had high heavy metal readings in their hair and urine analyses and were experiencing heavy metal toxicity effects. Diana had a range of symptoms and Landon was having difficulty in learning to speak and suffered chronic, recurrent viral infections (flu and colds). I started both of them on the Oral Chelation and Longevity Plus formulas.

After three months of consistently taking the formulas, Diana reported to me that she had increased energy, improved circulation, improved vision, and a decrease in headaches and angina pains. She stated, “I am amazed at the overall recovery of my body. My eyes have improved a lot. They are not so tired anymore and the muscles in the eyes do not seem to have the pulling sensation that I had before. Improvement in my immune system is also a big plus. I am no longer so weak that I pick up every cold or flu symptom that I come in contact with. Landon shows improvement in his immune system. I also notice that his speech is improving with the chelation.”

• Cindy Bright, 43, a patient with diabetes who presented with severe lack of mental clarity stated, “Since I’ve been on the Oral Chelation and Longevity Plus formulas I have no more ‘brain fog’ and the mental fuzziness is completely gone.”

• Terry Batt, in his 50’s, who had had a quadruple coronary artery bypass two years before and was experiencing pain and numbness in his right leg, wrote, “I have been taking the Oral Chelation and Longevity Plus formulas for three to four weeks. Since that time, I have noticed that the numbness in my right ankle is gone.”

Conclusion

Research has proven the benefits of chelation for cardiovascular disease, heavy metal toxicity, and other conditions. The number of physicians who are available to diagnose and treat advanced health problems and administer intravenous chelation continues to grow. This development, along with the recent advent of oral chelation, reflects the rapid changes occurring in U.S. health care. The transformation of medical practice is due to both public dissatisfaction with the “cut or medicate,” linear-delivery system of medicine and the demonstrated effectiveness of alternative and complementary therapies. Preventive health protocols (diet, exercise, and lifestyle modifications), chelation therapy, and nutritional sufficiency is the medicine of the future.

Maile and Greg Pouls new book, The Supplement Shopper, available in August, 1999, is a complete guide to nutritional supplements (Tiburon, CA: Future Medicine Publishing, 1999). Dr. Pouls’ can be contacted at 800-300-6712 or by email at info@extendedhealth.com.

Maile was the guest speaker on ‘Oral Chelation’ at the 1999 Holistic Dental Association Conference in Denver, Colorado, on May 14-16, 1999. The Holistic Dental Association (HDA) is an organization dedicated to providing physical, emotional and spiritual support to their patients and families, as well as a forum for the development and sharing of health-promoting therapies. James Kennedy, DDS, past president of the HDA and current editor of the HDA’s magazine, The Communicator, and Richard Shepard, DDS, executive director of HDA, both endorse the Oral Chelation/Longevity Plus formulas.

Oral Chelation and Longevity Plus nutritional formulas can be purchased at 800-300-6712. Professional and quantity discounts are available. Extended Health’s preliminary clinical studies are now available for review. Extended Health is appealing to doctors and health research centers interested in conducting related clinical studies. Please call Ms. Michele Payne at 800-300-6712.

References

64Klinghardt, D., MD, Ph.D. “Migraines, seizures, and mercury toxicity.” Alternative Medicine Digest 21 (December-January 1997-98), p. 64.

65Klinghardt, D., MD, Ph.D. “Amalgam/mercury detox as a treatment for chronic viral, bacterial, and fungal illnesses.” Annual Meeting of the International and American Academy of Clinical Nutrition, San Diego, CA, September 1996.